Cocaine-related syndrome and palatal reconstruction: report of a series of cases

Abstract Intranasal cocaine abuse may cause significant local ischaemic necrosis and destruction of the nasal and midfacial bones and soft tissue, leading to development of a cocaine-induced midline destructive lesion. Review of the English-language literature reveals only a few case reports describ...

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Bibliographic Details
Published in:International journal of oral and maxillofacial surgery 2007-08, Vol.36 (8), p.721-727
Main Authors: Di Cosola, M, Turco, M, Acero, J, Navarro-Vila, C, Cortelazzi, R
Format: Article
Language:English
Subjects:
Adult
Biological and medical sciences
cocaine
Cocaine-Related Disorders - complications
Cocaine-Related Disorders - psychology
Deglutition Disorders - chemically induced
Deglutition Disorders - diagnosis
Female
Fluoroscopy - instrumentation
Fluoroscopy - methods
Forearm - surgery
forearm flap
free flap
Humans
Male
Medical sciences
Middle Aged
Mouth Diseases - chemically induced
Mouth Diseases - surgery
Otorhinolaryngology. Stomatology
palatal reconstruction
Palate, Hard - drug effects
Palate, Hard - pathology
Palate, Hard - surgery
Reconstructive Surgical Procedures - methods
Recurrence
Skin Transplantation - methods
Speech Intelligibility
Surgery
Surgical Flaps
Treatment Outcome
Velopharyngeal Insufficiency - chemically induced
Velopharyngeal Insufficiency - surgery
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Summary:Abstract Intranasal cocaine abuse may cause significant local ischaemic necrosis and destruction of the nasal and midfacial bones and soft tissue, leading to development of a cocaine-induced midline destructive lesion. Review of the English-language literature reveals only a few case reports describing hard and/or soft palatal perforation related to cocaine inhalation. To date, among the reconstructive techniques of the palate, different surgical options have been reported such as local, regional and free flaps. Common prosthetic obturators have also been used. Presented here are six cases of cocaine abuse showing different types of cocaine-related palatal lesions treated with different surgical approaches including local and free flaps. Mean follow-up was 3 years. A surgical variation of Marshall's classic technique for insetting a free flap in such lesions is proposed.
ISSN:0901-5027
1399-0020
DOI:10.1016/j.ijom.2007.03.015