Coexistence of multiple sclerosis and brain tumours: Case report and review

In the present report, a review of the literature on the combination of multiple sclerosis and brain tumours is performed. Additionally, the frequency of such combination, possible etiopathogenetic mechanisms, current diagnostic criteria and treatment approaches are reviewed. Furthermore, the case o...

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Bibliographic Details
Published in:Interdisciplinary neurosurgery : Advanced techniques and case management 2020-03, Vol.19, p.100585, Article 100585
Main Authors: Sirko, Andrii, Dzyak, Lyudmila, Chekha, Ekaterina, Malysheva, Tetiana, Romanukha, Dmytro
Format: Article
Language:English
Subjects:
Anaplastic astrocytoma
Brain tumour
Demyelinating disease
Glioma
Multiple sclerosis
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Summary:In the present report, a review of the literature on the combination of multiple sclerosis and brain tumours is performed. Additionally, the frequency of such combination, possible etiopathogenetic mechanisms, current diagnostic criteria and treatment approaches are reviewed. Furthermore, the case of a 30-year-old man with multiple sclerosis and anaplastic astrocytoma of the right temporal lobe is described in detail. Specifically, the patient underwent a series of tests, including laboratory analyses of blood and cerebrospinal fluid, brain MRI in various modes, MR spectroscopy and excised tumour’s pathohistological and immunohistochemical examination. Results of the tests are reported here. A staged examination and treatment of the patient allowed the researchers to perform a correct diagnosis and obtain a satisfactory functional outcome.
ISSN:2214-7519
2214-7519
DOI:10.1016/j.inat.2019.100585