Preparation and evaluation of antioxidant capacity of Jackfruit ( Artocarpus heterophyllus Lam.) wine and its protective role against radiation induced DNA damage

• Published in: Industrial crops and products 2011-11, Vol.34 (3), p.1595-1601
• Main Authors: Jagtap, Umesh B., Waghmare, Shailesh R., Lokhande, Vinayak H., Suprasanna, Penna, Bapat, Vishwas A.
• Format: Article
• Language: English
• Subjects: Antioxidant capacity; DNA damage; Jackfruit ( Artocarpus heterophyllus Lam.); Total phenolic content; Wine
• ISSN: 0926-6690; 1872-633X
• DOI: 10.1016/j.indcrop.2011.05.025

► Preparation of wine from underutilized Jackfruit ( Artocarpus heterophyllus Lam.) pulp. ► Evaluation of the antioxidant properties of the jackfruit wine. ► Study DNA damage protecting activity of jackfruit wine. ► Development of Jackfruit wine as value added product from jackfruit. ► Provides opportunities to generate more profits and minimizes post harvest losses. Jackfruit is an underutilized edible fruit in the tropics and subtropics. The aim of this study was to produce wine from jackfruit pulp and to evaluate the total phenolic and flavonoid contents and antioxidant properties of the wine. The ability of scavenging free radicals was measured using 2,2-diphenyl-1-picrylhydrazyl (DPPH), ferric reducing antioxidant assay (FRAP), N, N-dimethyl-p-phenylendiamine (DMPD) and nitric oxide (NO) scavenging assays. Experimental results indicated that jackfruit wine was effective in DPPH radical scavenging (69.44 ± 0.34%), FRAP (0.358 optical density value, O.D.), DMPD (78.45 ± 0.05%) and NO (62.46 ± 0.45%) capacity. By the analysis of the high performance liquid chromatography coupled to diode array detector (HPLC-DAD), two phenolic compounds namely gallic acid and protocatechuic acid were identified. The jackfruit wine was also able to protect H 2O 2 + UV radiation and γ-radiation (100 Gy) induced DNA damage in pBR322 plasmid DNA. The antioxidant and DNA damage protecting properties of jackfruit wine confirmed health benefits when consumed and could become a valuable source of antioxidant rich neutraceuticals. Additionally, the wine could be a commercially valuable by-product for the jackfruit growers.