1,8-Naphthalimide-based fluorescent sensor with high selectivity and sensitivity for Zn2+ and its imaging in living cells

A novel 4-amino-1,8-naphthalimide-based fluorescent sensor with iminodiacetic acid as receptor, was developed and applied successfully to image Zn2+ in living cells. Under physiological pH conditions, it demonstrates high selectivity and sensitivity for sensing Zn2+ with about 34-fold enhancement in...

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Bibliographic Details
Published in:Inorganic chemistry communications 2019-03, Vol.101, p.117-120
Main Authors: Liu, Daying, Deng, Xinxin, Yin, Xin, Wang, Yuting, Guo, Jing, Chen, Jiatong, Yang, Guangming, He, Huarui
Format: Article
Language:English
Subjects:
Fluorescent sensor
Iminodiacetic acid
Naphthalimide
Zinc
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Summary:A novel 4-amino-1,8-naphthalimide-based fluorescent sensor with iminodiacetic acid as receptor, was developed and applied successfully to image Zn2+ in living cells. Under physiological pH conditions, it demonstrates high selectivity and sensitivity for sensing Zn2+ with about 34-fold enhancement in aqueous solution, with a characteristic emission band of 4-amino-1,8-naphthalimide with a green color centered at 550 nm. [Display omitted] •A new 1,8-naphthalimide-based fluorescent Zn2+ sensor was synthesized.•High selectivity and sensitivity for sensing Zn2+•It was applied successfully to image Zn2+ in living cells.
ISSN:1387-7003
1879-0259
DOI:10.1016/j.inoche.2019.01.023