Allergic contact dermatitis to topical antibiotics: Epidemiology, responsible allergens, and management

Topical antibiotics are widely used to treat cutaneous, ocular, and otic infections. Allergic contact dermatitis to topical antibiotics is a rare but well-documented side effect, especially in at-risk populations. The purpose of this article is to review the epidemiology, responsible allergens, and...

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Bibliographic Details
Published in:Journal of the American Academy of Dermatology 2008, Vol.58 (1), p.1-21
Main Authors: Gehrig, Kathryn A., MD, Warshaw, Erin M., MD, MS
Format: Article
Language:English
Subjects:
Administration, Topical
Age Distribution
Allergens - immunology
Anti-Bacterial Agents - adverse effects
Biological and medical sciences
Cross Reactions
Dermatitis, Allergic Contact - epidemiology
Dermatitis, Allergic Contact - etiology
Dermatitis, Allergic Contact - immunology
Dermatitis, Allergic Contact - therapy
Dermatology
Epidemiology
General aspects
Humans
Immunologic Tests
Medical sciences
Prevalence
Public health. Hygiene
Public health. Hygiene-occupational medicine
Risk Factors
Sex Distribution
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Summary:Topical antibiotics are widely used to treat cutaneous, ocular, and otic infections. Allergic contact dermatitis to topical antibiotics is a rare but well-documented side effect, especially in at-risk populations. The purpose of this article is to review the epidemiology, responsible allergens, and management of allergic contact dermatitis to topical antibiotics. Learning objective After completing this learning activity, participants should be able to describe the epidemiology of allergic contact dermatitis related to topical antibiotics; show knowledge of the most common allergenic topical antibiotics; and understand the allergenic cross-reactivity pattern amongst topical antibiotics.
ISSN:0190-9622
1097-6787
DOI:10.1016/j.jaad.2007.07.050