Patch testing a patient with allergic contact hand dermatitis who is taking infliximab

We report the case of a patient who developed allergic contact hand dermatitis while receiving infliximab infusions for psoriasis and psoriatic arthritis. Patch testing showed multiple positive allergens. To our knowledge, this is the first case report of successful patch testing in a patient receiv...

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Bibliographic Details
Published in:Journal of the American Academy of Dermatology 2008-07, Vol.59 (1), p.145-147
Main Authors: Rosmarin, David, MD, Bush, Michelle, MD, Scheinman, Pamela L., MD
Format: Article
Language:English
Subjects:
Antibodies, Monoclonal - therapeutic use
Arthritis, Psoriatic - drug therapy
Biological and medical sciences
Dermatitis, Allergic Contact - diagnosis
Dermatitis, Allergic Contact - etiology
Dermatitis, Allergic Contact - prevention & control
Dermatology
Gloves, Protective
Hand Dermatoses - chemically induced
Hand Dermatoses - diagnosis
Hand Dermatoses - prevention & control
Humans
Infliximab
Male
Medical sciences
Metallurgy
Metals
Middle Aged
Occupational Diseases - chemically induced
Occupational Diseases - diagnosis
Occupational Diseases - prevention & control
Occupational Exposure - analysis
Oils
Psoriasis - drug therapy
Skin Tests
Solvents
Tumor Necrosis Factor-alpha - antagonists & inhibitors
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Description
Summary:We report the case of a patient who developed allergic contact hand dermatitis while receiving infliximab infusions for psoriasis and psoriatic arthritis. Patch testing showed multiple positive allergens. To our knowledge, this is the first case report of successful patch testing in a patient receiving tumor necrosis factor–alpha (TNF-α) blockade therapy. TNF-α blockers do not necessarily suppress allergic contact hypersensitivity and are not an absolute contraindication to patch testing.
ISSN:0190-9622
1097-6787
DOI:10.1016/j.jaad.2008.02.016