Cardiovascular Magnetic Resonance Perfusion Imaging at 3-Tesla for the Detection of Coronary Artery Disease

• Published in: Journal of the American College of Cardiology 2007-06, Vol.49 (25), p.2440-2449
• Main Authors: Cheng, Adrian S.H., MBBS, MRCP, Pegg, Tammy J., MBChB, MRCP, Karamitsos, Theodoros D., MD, Searle, Nick, DCR(R), Jerosch-Herold, Michael, PhD, Choudhury, Robin P., DM, MRCP, Banning, Adrian P., MD, FRCP, FESC, Neubauer, Stefan, MD, FRCP, Robson, Matthew D., PhD, Selvanayagam, Joseph B., DPhil, FRACP, FESC
• Format: Article
• Language: English
• Subjects: Cardiovascular; Internal Medicine
• ISSN: 0735-1097; 1558-3597
• DOI: 10.1016/j.jacc.2007.03.028

Cardiovascular Magnetic Resonance Perfusion Imaging at 3-Tesla for the Detection of Coronary Artery Disease: A Comparison With 1.5-Tesla Adrian S. H. Cheng, Tammy J. Pegg, Theodoros D. Karamitosos, Matthew D. Robson, Nick Searle, Michael Jerosch-Herold, Robin P. Choudhury, Adrian P. Banning, Stefan Neubauer, Joseph B. Selvanayagam We aimed to establish the diagnostic accuracy of cardiovascular magnetic resonance (CMR) perfusion imaging at 3-Tesla (T) in patients with suspected coronary artery disease. Sixty-one patients referred for elective coronary angiography for investigation of exertional chest pain were studied (before angiogram) with first-pass perfusion CMR at both 1.5- and 3-T and at stress and rest. Quantitative coronary angiography served as the reference standard in defining the degree of coronary stenosis. We found that 3-T CMR perfusion imaging provided significantly greater diagnostic performance than at 1.5-T in identifying both significant single-vessel and multi-vessel disease.