Prospective Application of Pre-Defined Intravascular Ultrasound Criteria for Assessment of Intermediate Left Main Coronary Artery Lesions

• Published in: Journal of the American College of Cardiology 2011-07, Vol.58 (4), p.351-358
• Main Authors: de la Torre Hernandez, Jose M., MD, PhD, Hernández Hernandez, Felipe, MD, Alfonso, Fernando, MD, PhD, Rumoroso, Jose R., MD, PhD, Lopez-Palop, Ramon, MD, PhD, Sadaba, Mario, MD, Carrillo, Pilar, MD, PhD, Rondan, Juan, MD, PhD, Lozano, Iñigo, MD, PhD, Ruiz Nodar, Juan M., MD, PhD, Baz, Jose A., MD, Fernandez Nofrerias, Eduard, MD, Pajin, Fernando, MD, Garcia Camarero, Tamara, MD, Gutierrez, Hipolito, MD
• Format: Article
• Language: English
• Subjects: Cardiovascular; coronary artery disease; Internal Medicine; intravascular ultrasound; ischemia; left main coronary artery; stenosis
• ISSN: 0735-1097; 1558-3597
• DOI: 10.1016/j.jacc.2011.02.064

Objectives This study is a prospective validation of 6 mm2 as a minimum lumen area (MLA) cutoff value for revascularization of left main coronary artery (LMCA) lesions. Background Lesions involving the LMCA are prognostically relevant. Angiography has important limitations in the evaluation of LMCA lesions with intermediate severity. An MLA of 6 mm2 assessed by intravascular ultrasound has been proposed as a cutoff value to determine lesion severity, but there are no large studies evaluating the prospective application and safety of this approach. Methods We have designed a multicenter, prospective study. Consecutive patients with intermediate lesions in unprotected LMCA were evaluated with intravascular ultrasound. An MLA