Antenatal Therapy for Fetal Supraventricular Tachyarrhythmias

Standardized treatment of fetal tachyarrhythmia has not been established. This study sought to evaluate the safety and efficacy of protocol-defined transplacental treatment for fetal supraventricular tachycardia (SVT) and atrial flutter (AFL). In this multicenter, single-arm trial, protocol-defined...

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Bibliographic Details
Published in:Journal of the American College of Cardiology 2019-08, Vol.74 (7), p.874-885
Main Authors: Miyoshi, Takekazu, Maeno, Yasuki, Hamasaki, Toshimitsu, Inamura, Noboru, Yasukochi, Satoshi, Kawataki, Motoyoshi, Horigome, Hitoshi, Yoda, Hitoshi, Taketazu, Mio, Nii, Masaki, Hagiwara, Akiko, Kato, Hitoshi, Shimizu, Wataru, Shiraishi, Isao, Sakaguchi, Heima, Ueda, Keiko, Katsuragi, Shinji, Yamamoto, Haruko, Sago, Haruhiko, Ikeda, Tomoaki
Format: Article
Language:English
Subjects:
adverse event
atrial flutter
fetal echocardiography
fetal tachyarrhythmia
supraventricular tachycardia
transplacental treatment
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Summary:Standardized treatment of fetal tachyarrhythmia has not been established. This study sought to evaluate the safety and efficacy of protocol-defined transplacental treatment for fetal supraventricular tachycardia (SVT) and atrial flutter (AFL). In this multicenter, single-arm trial, protocol-defined transplacental treatment using digoxin, sotalol, and flecainide was performed for singleton pregnancies from 22 to 
ISSN:0735-1097
1558-3597
DOI:10.1016/j.jacc.2019.06.024