Transcatheter Closure of Atrial and Ventricular Septal Defects

• Published in: Journal of the American College of Cardiology 2022-06, Vol.79 (22), p.2247-2258
• Main Authors: Turner, Mariel E., Bouhout, Ismail, Petit, Christopher J., Kalfa, David
• Format: Article
• Language: English
• Subjects: atrial septal defect; congenital heart disease; interventional cardiology; transcatheter device closure; ventricular septal defect
• ISSN: 0735-1097; 1558-3597
• DOI: 10.1016/j.jacc.2021.08.082

The field of congenital interventional cardiology has experienced tremendous growth in recent years. Beginning with the development of early devices for transcatheter closure of septal defects in the 1970s and 1980s, such technologies have evolved to become a mainstay of treatment for many atrial septal defects (ASDs) and ventricular septal defects (VSDs). Percutaneous device closure is now the preferred approach for the majority of secundum ASDs. It is also a viable treatment option for selected VSDs, though limitations still exist. In this review, the authors describe the current state of transcatheter closure of ASDs and VSDs in children and adults, including patient selection, procedural approach, and outcomes. Potential areas for future evolution and innovation are also discussed. [Display omitted] •Transcatheter device closure is the preferred approach for most secundum atrial septal defects.•Ventricular septal defects are more often treated surgically, but transcatheter closure is an option in selected cases.•Novel devices and technologies will expand the range of defects in cardiac septation that can be closed by catheter-based techniques.