Interventions for Congenital Atrioventricular Valve Dysfunction

• Published in: Journal of the American College of Cardiology 2022-06, Vol.79 (22), p.2259-2269
• Main Authors: Barry, Oliver M., Bouhout, Ismail, Kodali, Susheel K., George, Isaac, Rosenbaum, Marlon S., Petit, Christopher J., Kalfa, David
• Format: Article
• Language: English
• Subjects: congenital heart disease; interventional cardiology; mitral valve replacement; transcatheter heart valve; tricuspid valve replacement
• ISSN: 0735-1097; 1558-3597
• DOI: 10.1016/j.jacc.2021.08.083

Innovation and creativity have led to tremendous advancements in the care and management of patients with congenital heart disease (CHD) that have resulted in considerably increased survival. Catheter-based interventions have contributed significantly to these advancements. However, catheter-based interventions for congenital lesions of the atrioventricular (AV) valves have been limited in scope and effectiveness mainly because of patient size and anatomical challenges. Thus, surgical repair and replacement for congenital AV valve lesions have remained the preferred therapy. However, the ongoing transcatheter heart valve revolution has led to techniques and technologies that are changing the landscape, particularly for adult CHD patients. Many devices for AV valve repair and replacement are being studied in adult patients without CHD, and translation of select practices to CHD patients has begun, with many more to come. Transcatheter AV valve interventions represent exciting opportunities for the growing numbers of adult CHD patients. [Display omitted] •Catheter interventions for congenital AV valve dysfunction have been limited in scope and effectiveness.•Experience with transcatheter AV valve replacement and repair is increasingly translated to patients with congenital anomalies.•These innovative techniques represent exciting opportunities to benefit patients with CHD.