Thromboembolic Risk in Atrial Fibrillation Patients With Left Atrial Scar Post-Extensive Ablation

This study evaluated the association of the post-ablation scar with stroke risk in patients undergoing atrial fibrillation (AF) ablation. Late gadolinium enhancement–cardiac magnetic resonance studies have reported a direct association between pre-ablation left atrial scar and thromboembolic events...

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Bibliographic Details
Published in:JACC. Clinical electrophysiology 2021-03, Vol.7 (3), p.308-318
Main Authors: Mohanty, Sanghamitra, Trivedi, Chintan, Della Rocca, Domenico G., Baqai, Faiz M., Anannab, Alisara, Gianni, Carola, MacDonald, Bryan, Quintero Mayedo, Angel, Bassiouny, Mohamed, Gallinghouse, G. Joseph, Burkhardt, John D., Horton, Rodney, Al-Ahmad, Amin, Di Biase, Luigi, Natale, Andrea
Format: Article
Language:English
Subjects:
atrial fibrillation
catheter ablation
left atrial scar
stroke
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Summary:This study evaluated the association of the post-ablation scar with stroke risk in patients undergoing atrial fibrillation (AF) ablation. Late gadolinium enhancement–cardiac magnetic resonance studies have reported a direct association between pre-ablation left atrial scar and thromboembolic events in patients with AF. Consecutive patients with AF were classified into 2 groups based on the type of ablation performed at the first procedure. Group 1 involved limited ablation (isolation of pulmonary veins, left atrial posterior wall, and superior vena cava); and group 2 involved extensive ablation (limited ablation + ablation of nonpulmonary vein triggers from all sites except left atrial appendage). During the repeat procedure, post-ablation scar (region with bipolar voltage amplitude 
ISSN:2405-500X
2405-5018
DOI:10.1016/j.jacep.2020.08.035