Type 1 Diabetes as a Risk Factor for Impaired Vitamin D Status in a Multi-Ethnic Cohort of Canadian Adolescents

Abstract Objectives To evaluate type 1 diabetes as a risk factor for vitamin D status in an established, multi-ethnic adolescent cohort in relation to a healthy Canadian population. Methods A total of 271 subjects, 12 to 18 years of age, with established type 1 diabetes mellitus, were recruited for...

Full description

Saved in:
Bibliographic Details
Published in:Canadian journal of diabetes 2012-12, Vol.36 (6), p.314-319
Main Authors: Yeshayahu, Yonatan, MD, Sochett, Etienne B., MB, ChB, Deda, Livia, MSc, Sud, Shama, MSc, Mahmud, Farid H., MD
Format: Article
Language:English
Subjects:
adolescents
diabète de type 1
Endocrinology & Metabolism
Other
type 1 diabetes
vitamin D
vitamine D
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Abstract Objectives To evaluate type 1 diabetes as a risk factor for vitamin D status in an established, multi-ethnic adolescent cohort in relation to a healthy Canadian population. Methods A total of 271 subjects, 12 to 18 years of age, with established type 1 diabetes mellitus, were recruited for this cross-sectional study. Demographic and clinical data were collected, and 25-hydroxyvitamin D (25-OHD) levels using liquid chromatography-mass spectrometry (LC-MS/MS) were measured. Normative Canadian-based population data were used as a reference group. Results Lower rates of vitamin D sufficiency were observed in adolescents with type 1 diabetes when compared to healthy Canadian adolescents. For the type 1 diabetes group 14.0% of subjects were vitamin D sufficient (>75.0 nmol/L) and 32.8% were deficient (≤37.5 nmol/L), compared to 35.2% and 11.8%, respectively in the Canadian reference population (p
ISSN:1499-2671
2352-3840
DOI:10.1016/j.jcjd.2012.10.002