Poly(1,3-trimethylene carbonate) networks as a resorbable scleral buckle

Currently non-resorbable scleral buckles are used to repair a retinal detachment in the eye. In contrast to a non-resorbable implant, a resorbable implant will disappear after it has fulfilled its function. PTMC scleral buckles were implanted in six rabbits and explanted 10 weeks later. Histological...

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Bibliographic Details
Published in:Journal of controlled release 2008-12, Vol.132 (3), p.e51-e52
Main Authors: de Vos, S.V.N., Koopmans, S.A., Hooymans, J.M.M., Feijen, J., Grijpma, D.W.
Format: Article
Language:English
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Summary:Currently non-resorbable scleral buckles are used to repair a retinal detachment in the eye. In contrast to a non-resorbable implant, a resorbable implant will disappear after it has fulfilled its function. PTMC scleral buckles were implanted in six rabbits and explanted 10 weeks later. Histological analysis showed a mild tissue response, the degradation rate was up to 9.2 μm/day. Based on these results, it is expected that PTMC is a suitable material for scleral buckle application.
ISSN:0168-3659
1873-4995
DOI:10.1016/j.jconrel.2008.09.035