Loading…

Computer Aided Diagnostics and Local Drug Treatment (Case Reports)

The surgical use of navigation procedures for static or dynamic intervention is widespread. Little is known about the use of navigation procedures in diagnostic and locoregional drug therapy. We aimed to demonstrate the methods used during computer aided surgery (CAS) that can be applied for diagnos...

Full description

Saved in:
Bibliographic Details
Published in:Journal of dentistry 2024-08, Vol.147, p.105177, Article 105177
Main Authors: Pinter, Gabor Tamas, Fabian, Zoltan, Hermann, Peter, Bogdan, Sandor
Format: Article
Language:English
Subjects:
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The surgical use of navigation procedures for static or dynamic intervention is widespread. Little is known about the use of navigation procedures in diagnostic and locoregional drug therapy. We aimed to demonstrate the methods used during computer aided surgery (CAS) that can be applied for diagnostic and therapeutic purposes based on two clinical cases. A 34-year-old female patient presented who had received radio-chemotherapy for adenoid cystic carcinoma of the soft palate 12 years prior. MRI showed a slowly growing terime next to the foramen rotundum close to the pterygopalatine fossa, suggesting the presence of tumor recidiva. A CT-based surgical template with dental support was prepared using the stereolithographic technique to successfully perform biopsy from a difficult to reach anatomical region. Template-guided aspiration cytology was performed from the lesion identified by MRI, which was positive for adenocystic carcinoma. Based on the results, surgical excision was performed. A 15-year-old male patient presented with a history of swelling and pain on the right side of the nasal cavity, detected one year earlier. CT scans showed a cyst-like lesion extending into the sinus and partially into the lower frontal part of the nasal cavity and extending from the vestibule of the frontal region to the level of the right molar in the mouth, with a fluid-filled cyst that also involved the palate. Histologic examination confirmed a central giant cell granuloma. Reduction of the right benign maxillary tumor was performed. Based on the results of histopathological examination, local steroid therapy was applied. A CT-based stereolithographic surgical template with dental support was used for precise targeting. Infiltration with 40 mg Kenalog (triamcinolone acetonide) was performed under local anesthesia using the template for one year postoperatively, with monthly recurrence. The digital methods used in navigated surgical procedures can also be used to design and implement diagnostic and drug treatment procedures.
ISSN:0300-5712
1879-176X
DOI:10.1016/j.jdent.2024.105177