Biosynthesis of copper nanoparticles; its characterization and efficacy against human pathogenic bacterium

• Published in: Journal of environmental chemical engineering 2016-06, Vol.4 (2), p.2163-2169
• Main Authors: Patel, B.H., Channiwala, M.Z., Chaudhari, S.B., Mandot, A.A.
• Format: Article
• Language: English
• Subjects: Biosynthesis method; Characterization; Copper nano-particles; Ocimum sanctum extract
• ISSN: 2213-3437; 2213-3437
• DOI: 10.1016/j.jece.2016.03.046

•Copper nano particles were prepared by environmentally friendly bio-reduction process from copper salt solution.•The prepared particles characterized by UV–vis spectroscopy, FTIR and EDS technique confirmed the presence of copper nano-particles. The Z-average diameter of synthesized copper nano-particles was found to be 122.7nm with polydispersity index (PDI) of 0.116.•Highly stable copper nano particles with good antibacterial activity were prepared by a sustainable technique for medicinal applications. Synthesis of nano-material with the controlled size and shape is the prime concern of research in nanotechnology. Recently, biosynthesis of metallic nano-particles has gained popularity owing to its eco-friendliness. Use of natural plant extracts in the preparation of nano-particles provides advancement over chemical and physical methods, due to its t is cost effectiveness and environment friendly nature. In the present work, copper nano-particles have been synthesized with simple and green technique by using Ocimum sanctum plant leaf extract as reducer as well as stabilizer. The size and shape of synthesized nano-particles were pigeonholed by particle size analyzer and SEM, further were characterized by EDS and FT-IR spectral technique for their elemental and chemical composition. The experimental results showed copper nano-particles having Z-average diameter of 122.7nm with higher stability and significantly higher antibacterial activities.