Magnetically separable iron oxide nanoparticle for reduction of nitroarenes and reductive amination of carbonyl compounds in aqueous medium

• Published in: Journal of industrial and engineering chemistry (Seoul, Korea) Korea), 2024-11
• Main Authors: Kachore, Ankit, Bala, Ekta, Aggarwal, Varun, Singh, Hemant, Saima, Suleiman, Mohamed Hammad Adam, Selvaraj, Manickam, Verma, Praveen Kumar
• Format: Article
• Language: English
• Subjects: Heterogeneous catalyst; Hydrazine Hydrate; Magnetically Separable; Nitro Reduction; Reductive Amination; Water
• ISSN: 1226-086X
• DOI: 10.1016/j.jiec.2024.11.034

[Display omitted] •Magnetically separable, recyclable, iron based heterogeneous catalyst.•Reduction of nitroarenes (including water contaminants) in water.•Hydrazine hydrate as clean and green hydrogen source.•Reductive amination of synthesized amines with carbonyls.•Wide substrate scope (including pharmaceuticals), no column chromatographic purification. Novel biogenic iron oxide nanoparticles (Fe@BNPs) were synthesised using Adiantum capillus-veneris extract (aq.) as a capping and stabilising agent and meticulously characterized using FT-IR, UV–vis, FESEM, EDX, TEM, XPS, and XRD techniques. Subsequently, Fe@BNPs were employed for the catalytic reduction of various nitroaromatic compounds employing hydrazine hydrate under benign reaction conditions in water. Notably, the magnetic behaviour of Fe@BNPs enabled their facile recovery using an external magnet, facilitating catalyst reuse in multiple cycles with minimal leaching or loss of activity. Furthermore, the versatility of Fe@BNPs was demonstrated through their application in reductive amination reactions, employing nitro-reduced primary amines and carbonyl compounds. This ligand-free approach offers significant advantages including environmental sustainability, green solvent, exceptional product yields, straightforward workup procedures, efficient purification, gram-scale reactions and excellent catalyst reusability.