ANCA-negative granulomatosis with polyangiitis presenting with orbital apex syndrome and recurrent pachymeningitis: A case report

Highlights • An unusual case of GPA with diverse neurological manifestations • The patient presented orbital apex syndrome and orbital pseudotumor. • He also exhibited an ANCA-negative granulomatous vasculitis in the brain. • Administration of prednisolone resulted in improvement of clinical manifes...

Full description

Saved in:
Bibliographic Details
Published in:Journal of the neurological sciences 2016-09, Vol.368, p.175-177
Main Authors: Hisahara, Shin, Yamada, Minoru, Matsuura, Yousuke, Tsuda, Emiko, Akiyama, Yukinori, Saitoh, Masaki, Kawamata, Jun, Mikuni, Nobuhiro, Shimohama, Shun
Format: Article
Language:English
Subjects:
Aged
Anti-neutrophil cytoplasm antibodies (ANCA)
Antibodies, Antineutrophil Cytoplasmic - metabolism
Brain - diagnostic imaging
Brain - pathology
Cranial Nerve Diseases - diagnosis
Cranial Nerve Diseases - drug therapy
Cranial Nerve Diseases - pathology
Cranial Nerve Diseases - physiopathology
Diagnosis, Differential
Granulomatosis with polyangiitis (GPA)
Granulomatosis with Polyangiitis - diagnosis
Granulomatosis with Polyangiitis - drug therapy
Granulomatosis with Polyangiitis - pathology
Granulomatosis with Polyangiitis - physiopathology
Humans
Male
Meningitis - diagnosis
Meningitis - drug therapy
Meningitis - pathology
Meningitis - physiopathology
Neurology
Orbital apex syndrome (OAS)
Orbital pseudotumor
Pachymeningitis
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Highlights • An unusual case of GPA with diverse neurological manifestations • The patient presented orbital apex syndrome and orbital pseudotumor. • He also exhibited an ANCA-negative granulomatous vasculitis in the brain. • Administration of prednisolone resulted in improvement of clinical manifestations. • Neurological involvement of limited form of GPA is discussed.
ISSN:0022-510X
1878-5883
DOI:10.1016/j.jns.2016.07.013