Amyotrophic lateral sclerosis with frontotemporal dementia (ALS-FTD) syndrome as a phenotype of Creutzfeldt-Jakob disease (CJD)? A case report

Highlights • A case of CJD similar to ALS with frontotemporal dementia (ALS-FTD) is reported. • ALS-FTD like symptoms may be an integral part of CJD. • RT-QUIC may complement the weakness of 14-3-3 protein, tau protein and MR images.

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Bibliographic Details
Published in:Journal of the neurological sciences 2017-01, Vol.372, p.444-446
Main Authors: Yaguchi, Hiroaki, Takeuchi, Akiko, Horiuchi, Kazuhiro, Takahashi, Ikuko, Shirai, Shinnichi, Akimoto, Sachiko, Satoh, Katsuya, Moriwaka, Fumio, Yabe, Ichiro, Sasaki, Hidenao
Format: Article
Language:English
Subjects:
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Amyotrophic Lateral Sclerosis - complications
Amyotrophic Lateral Sclerosis - diagnostic imaging
Amyotrophic lateral sclerosis with frontotemporal dementia (ALS-FTD)
Creutzfeldt-Jakob disease (CJD)
Creutzfeldt-Jakob Syndrome - physiopathology
Diffusion Magnetic Resonance Imaging
Electromyography
Frontotemporal Dementia - complications
Frontotemporal Dementia - diagnostic imaging
Humans
Male
Neurology
Real-time quaking-induced conversion (RT-QUIC)
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Description
Summary:Highlights • A case of CJD similar to ALS with frontotemporal dementia (ALS-FTD) is reported. • ALS-FTD like symptoms may be an integral part of CJD. • RT-QUIC may complement the weakness of 14-3-3 protein, tau protein and MR images.
ISSN:0022-510X
1878-5883
DOI:10.1016/j.jns.2016.10.038