Fatal ischemic stroke caused by cerebral small arteritis in a patient with giant cell arteritis

•A case of recurrent and fatal ischemic infarctions in a GCA patient is reported.•Multiple intracranial large-artery stenoses on MRA were found.•On autopsy, inflammations were scarce in large and medium-sized arteries.•Lymphocytic infiltrations in cerebral small arteries were observed.

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Bibliographic Details
Published in:Journal of the neurological sciences 2018-08, Vol.391, p.22-24
Main Authors: Nakano, Fumi, Ueno, Yuji, Suda, Akimitsu, Takanashi, Masashi, Yamashita, Atsushi, Abe, Yoshiyuki, Kon, Takayuki, Miyamoto, Nobukazu, Yamashiro, Kazuo, Tanaka, Ryota, Naito, Toshio, Yao, Takashi, Tamura, Naoto, Hattori, Nobutaka
Format: Article
Language:English
Subjects:
Aged
Brain - diagnostic imaging
Brain - pathology
Brain Ischemia - drug therapy
Brain Ischemia - etiology
Brain Ischemia - pathology
Fatal Outcome
Giant cell arteritis
Giant Cell Arteritis - complications
Giant Cell Arteritis - drug therapy
Giant Cell Arteritis - pathology
Humans
Intracranial artery stenosis
Male
Recurrence
Steroid
Stroke
Stroke - drug therapy
Stroke - etiology
Stroke - pathology
Vasculitis, Central Nervous System - complications
Vasculitis, Central Nervous System - drug therapy
Vasculitis, Central Nervous System - pathology
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Description
Summary:•A case of recurrent and fatal ischemic infarctions in a GCA patient is reported.•Multiple intracranial large-artery stenoses on MRA were found.•On autopsy, inflammations were scarce in large and medium-sized arteries.•Lymphocytic infiltrations in cerebral small arteries were observed.
ISSN:0022-510X
1878-5883
DOI:10.1016/j.jns.2018.05.010