Paraneoplastic myelopathy with amphiphysin autoantibodies and lobular breast carcinoma in situ

•Paraneoplastic neurologic syndromes may occur with carcinoma in-situ.•MRI breast can reveal in-situ malignancy not detected on other screening modalities.•Paraneoplastic myelopathies are associated with hallmark MRI findings.

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Bibliographic Details
Published in:Journal of the neurological sciences 2022-01, Vol.432, p.120086, Article 120086
Main Authors: Alexandres, Christina A., Tremblay, Matthew A., Klassen, Christine L., Degnim, Amy, Flanagan, Eoin P.
Format: Article
Language:English
Subjects:
Antibody
Autoantibodies
Breast cancer
Breast Carcinoma In Situ
Breast Neoplasms - complications
Encephalomyelitis
Female
Humans
Middle Aged
Myelitis
Nerve Tissue Proteins
Paraneoplastic Syndromes
Spinal cord
Spinal Cord Diseases
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Description
Summary:•Paraneoplastic neurologic syndromes may occur with carcinoma in-situ.•MRI breast can reveal in-situ malignancy not detected on other screening modalities.•Paraneoplastic myelopathies are associated with hallmark MRI findings.
ISSN:0022-510X
1878-5883
DOI:10.1016/j.jns.2021.120086