Synthesis of nanocatalyst Pd immobilized on ZPD as efficient and reusable for Sonogashira cross-coupling reaction

• Published in: Journal of organometallic chemistry 2022-12, Vol.980-981, p.122497, Article 122497
• Main Authors: Najafi, Mehdi, Alinezhad, Heshmatollah, Ghasemi, Shahram, Yeganeh-Salman, Elham
• Format: Article
• Language: English
• Subjects: Metal-organic framework; Pd nanoparticles; Post-synthetic modification; Sonogashira cross-coupling reaction
• ISSN: 0022-328X; 1872-8561
• DOI: 10.1016/j.jorganchem.2022.122497

•ZPD as a metal – organic framework was prepared hydrothermally as substrate for catalyst.•Pd@ZPD nanoparticles were fabricated as efficient catalyst for Sonogashira cross-coupling reaction.•Pd@ZPD catalyst reserved its structure without considerable leaching of Pd during the process.•The heterogeneous catalyst can be recycled and reused six times without significant in reaction yield. ZPD as one type of MOF is based on zinc ions, in the structure of which 2,5 pyridine dicarboxylic acid (pydc) ligand is present. A heterogeneous catalyst consisting of palladium nanoparticles (NPs) loaded on Zn4(pydc)4(DMF)2·3DMF support (Pd@ZPD) was synthesized by incipient wet impregnation procedure and its catalytic activity in the Sonogashira cross-reaction was investigated. Pd@ZPD has some important advantages such as high surface area and porosity, high thermal stability, and good tolerance for air and moisture. Using inductively coupled plasma-optical emission spectroscopy (ICP-OES), the content of Pd loaded into the Pd@ZPD nanocatalyst was obtained at nearly 2.85wt.%. The heterogeneous catalyst could be used six times without losing its catalytic activity. The catalyst is easily separated from the reaction products without a significant decrease in the catalytic activity and reaction yield which makes it suitable for practical applications.