Trends Toward Earlier Puberty Timing in Girls and Its Likely Mechanisms

This is the first of two installments examining early puberty in girls. The first paper will discuss secular trends in onset of puberty and the possible mechanisms to explain these developments. The potential etiologies examined will include the role of endocrine-disrupting chemicals and obesogens,...

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Bibliographic Details
Published in:Journal of pediatric & adolescent gynecology 2022-10, Vol.35 (5), p.527-531
Main Authors: Cheng, Tuck Seng, Ong, Ken K., Biro, Frank M.
Format: Article
Language:English
Subjects:
Adult
Biological Products
Body Mass Index
Female
Humans
Obesity - complications
Puberty
Puberty, Precocious - chemically induced
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Summary:This is the first of two installments examining early puberty in girls. The first paper will discuss secular trends in onset of puberty and the possible mechanisms to explain these developments. The potential etiologies examined will include the role of endocrine-disrupting chemicals and obesogens, the impact of body mass index and obesity, genetic and biologic pathways, and the influence of lifestyle behaviors. The second paper of the two-part series will examine the potential health impacts of early puberty on young and adult women and offer suggestions for clinical management and public health prevention.
ISSN:1083-3188
1873-4332
DOI:10.1016/j.jpag.2022.04.009