Modulation of gamma-irradiation and carbon tetrachloride induced oxidative stress in the brain of female rats by flaxseed oil

The activity of flaxseed oil (FSO) on gamma-irradiation (7Gy) and/or carbon tetrachloride (CCl4) induced acute neurotoxicity in rats' brain was investigated. The results revealed a significant decrease (p

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Bibliographic Details
Published in:Journal of photochemistry and photobiology. B, Biology Biology, 2016-08, Vol.161, p.91-99
Main Authors: Ismail, Amel F.M., Salem, Asmaa A.M., Eassawy, Mamdouh M.T.
Format: Article
Language:English
Subjects:
and trace elements
Animals
Antioxidants - metabolism
Brain - drug effects
Brain - metabolism
Brain - radiation effects
carbon tetrachloride
Carbon Tetrachloride - toxicity
Catalase - metabolism
Cytokines - analysis
Enzyme-Linked Immunosorbent Assay
Female
Flaxseed Oil
Gamma Rays
Glutathione - metabolism
Glutathione Peroxidase - metabolism
Linseed Oil - chemistry
Linseed Oil - pharmacology
Malondialdehyde - metabolism
Metals - analysis
Nitric Oxide - metabolism
Nitric Oxide Synthase Type II - genetics
Nitric Oxide Synthase Type II - metabolism
Oxidative Stress - drug effects
Oxidative Stress - radiation effects
pro-inflammatory cytokines
Rats
Rats, Wistar
Spectrophotometry, Atomic
Superoxide Dismutase - metabolism
Xanthine Oxidase - genetics
Xanthine Oxidase - metabolism
xanthine oxidase and inducible nitric oxide synthase gene expression
γ-irradiation
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Summary:The activity of flaxseed oil (FSO) on gamma-irradiation (7Gy) and/or carbon tetrachloride (CCl4) induced acute neurotoxicity in rats' brain was investigated. The results revealed a significant decrease (p
ISSN:1011-1344
1873-2682
DOI:10.1016/j.jphotobiol.2016.04.031