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Immunomodulatory potentials of saccharomyces cerevisiae in mitigation of testicular heat stress alterations

Change in global temperature has become an important factor affecting reproduction both in humans and livestock. This study investigated the mitigative effect of Saccharomycescerevisiae on testicular histo-architecture and function in male albino rats subjected to increased localized thermal tempera...

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Bibliographic Details
Published in:Journal of reproductive immunology 2023-09, Vol.159, p.104057, Article 104057
Main Authors: Mbegbu, Edmund C., Ikele, Chinelo G., Obidike, Ikechukwu R., Parrish, John J.
Format: Article
Language:English
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Summary:Change in global temperature has become an important factor affecting reproduction both in humans and livestock. This study investigated the mitigative effect of Saccharomycescerevisiae on testicular histo-architecture and function in male albino rats subjected to increased localized thermal temperature. Twenty mature male albino rats were divided into four groups of five rats each and treated once daily per os for a period of five weeks. The control (group A) and positive control (group B) maintained an ambient temperature (24-30°C), with group B treated with Saccharomyces cerevisiae. Groups C & D were exposed to a temperature of 43°C for 15mins thrice at 2 days intervals. Supplementation with Saccharomycescerevisiae was done in group D. Exposure to heat increased (P
ISSN:0165-0378
1872-7603
DOI:10.1016/j.jri.2023.104057