Dasatinib induces long-term remission in imatinib-resistant Philadelphia chromosome-positive acute megakaryoblastic leukemia but fails to prevent development of central nervous system progression

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Bibliographic Details
Published in:Leukemia research 2010-09, Vol.34 (9), p.e254-e256
Main Authors: Papageorgiou, Sotirios G, Pappa, Vasiliki, Economopoulou, Christina, Tsirigotis, Panagiotis, Konsioti, Frida, Ionnidou, Eleni-Dikaia, Chondropoulos, Spyros, Vasilatou, Diamantina, Papageorgiou, Efstathios, Economopoulos, Theofanis, Dervenoulas, John
Format: Article
Language:English
Subjects:
Antineoplastic Agents - therapeutic use
Benzamides
Central Nervous System Neoplasms - secondary
Dasatinib
Drug Resistance, Neoplasm
Hematology, Oncology and Palliative Medicine
Humans
Imatinib Mesylate
Karyotyping
Leukemia, Megakaryoblastic, Acute - drug therapy
Leukemia, Megakaryoblastic, Acute - genetics
Leukemia, Megakaryoblastic, Acute - pathology
Male
Middle Aged
Philadelphia Chromosome
Piperazines - therapeutic use
Pyrimidines - therapeutic use
Remission Induction
Thiazoles - therapeutic use
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ISSN:0145-2126
1873-5835
DOI:10.1016/j.leukres.2010.03.032