Effects of in vitro simulated gastrointestinal digestion on the antioxidant, α-glucosidase and α-amylase inhibitory activities of water-soluble polysaccharides from Opilia amentacea roxb fruit

Opilia amentacea is a medicinal plant commonly used by the West African traditional healers to cure a wide variety of ailments and per-capita consumption of these fruits could help to improve the health system. This study was intended to investigate the impacts of in vitro gastrointestinal digestion...

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Bibliographic Details
Published in:Food science & technology 2019-08, Vol.111, p.774-781
Main Authors: Kasipandi, Muniyandi, Manikandan, Ayyapan, Sreeja, Puthanpura Sasidharan, Suman, Thamburaj, Saikumar, Sathyanarayanan, Dhivya, Sivaraj, Parimelazhagan, Thangaraj
Format: Article
Language:English
Subjects:
Antioxidant
Opilia amentacea
α-amylase
α-glucosidase
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Summary:Opilia amentacea is a medicinal plant commonly used by the West African traditional healers to cure a wide variety of ailments and per-capita consumption of these fruits could help to improve the health system. This study was intended to investigate the impacts of in vitro gastrointestinal digestion on the free radicals, α-glucosidase and α-amylase inhibiting properties of O. amentacea fruit polysaccharides (OAFP). The pre-digested (864 mg glucose equivalents/g of sample) and gastric digested (880 mg glucose equivalents/g of sample) OAFP showed higher sugar content than pancreatic digested OAFP (101 mg glucose equivalents/g of sample). The antioxidant, α-glucosidase and α-amylase inhibitory activities of OAFP were significantly increased after gastric digestion. This evidently proved that OAFPs can be easily digested and made readily available for the intestine absorption. However, the sugar content was decreased after pancreatic digestion indicating the bioactive potential of OAFP as an antioxidant and antihyperglycemic, which could be considered as a promising candidate for functional foods. •Opilia amentacea fruits are effective to prevent the oxidative stress and hyperglycemic associated disorders.•The fruits polysaccharides were easily bioaccessible in the intestine.•The fruits polysaccharides were effective inhibited the α-glucosidase and α-amylase enzymes.•Functional food from O. amentacea could be used in the human diet.
ISSN:0023-6438
1096-1127
DOI:10.1016/j.lwt.2019.05.079