Simple fabrication of silver hybridized porous chitosan-based patch for transdermal drug-delivery system

To improve the physiochemical properties of bio-patch materials, silver compounds of various concentrations were synthesized in chitosan solution and formed to silver hybridized porous chitosan structures. We examined various properties such as morphology, crystallization intensity, mechanical stren...

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Bibliographic Details
Published in:Materials letters 2013-03, Vol.95, p.48-51
Main Authors: Hye Kim, Ji, Il Kim, Seung, Kwon, Il-Bum, Hyun Kim, Mi, Ik Lim, Jin
Format: Article
Language:English
Subjects:
chitosan
crystallization
drugs
molecular weight
Porous chitosan patch
silver
Silver acetate
silver nitrate
Silver particles
sodium
sterilizing
Transdermal drug-delivery system
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Summary:To improve the physiochemical properties of bio-patch materials, silver compounds of various concentrations were synthesized in chitosan solution and formed to silver hybridized porous chitosan structures. We examined various properties such as morphology, crystallization intensity, mechanical strength, hydrophilic ratio and drug-delivery efficiency. We ascertained that it was optimal to combine silver nitrate of 3%, chitosan of 1% (molecular weight
ISSN:0167-577X
1873-4979
DOI:10.1016/j.matlet.2012.12.078