Nanostructure, porosity and tensile strength of PVA/Hydroxyapatite composite nanofiber for bone tissue engineering

Hydroxyapatite [HAp, Ca10(PO4)6(OH)2] was successfully synthesized using natural minerals, precisely limestone from Druju Indonesia. As a bone scaffold compound, HAp has a weakness of low mechanical properties therefore it needs to be mixed with polymeric materials, such as polyvinyl alcohol (PVA) t...

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Bibliographic Details
Main Authors: Hartatiek, Yudyanto, Wuriantika, M.I., Utomo, Joko, Nurhuda, M., Masruroh, Santjojo, D.J.D.H.
Format: Conference Proceeding
Language:English
Subjects:
Hydroxyapatite
Nanofiber
Nanostructure
Polyvinyl alcohol
Porosity
Tensile strength
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Summary:Hydroxyapatite [HAp, Ca10(PO4)6(OH)2] was successfully synthesized using natural minerals, precisely limestone from Druju Indonesia. As a bone scaffold compound, HAp has a weakness of low mechanical properties therefore it needs to be mixed with polymeric materials, such as polyvinyl alcohol (PVA) to improve its mechanical properties. The PVA/HAp composites nanofiber have successfully synthesized using the electrospinning method and analyzed including nanostructure, porosity and tensile strength of nanofiber. The diameter of PVA/HAp composites nanofiber in 173 to 234 nm, porosity in 62 to 74%, and tensile strength in 6.96 to 15.85 MPa. Increasing of HAp cocentrasion increase of tensile strength, SEM showed an increase in HAp concentration (0%−20%) causing a decrease in the average diameter of the fiber. The characteristics of PVA/HAp composite nanofiber can be applied as a scaffold in bone tissue engineering.
ISSN:2214-7853
2214-7853
DOI:10.1016/j.matpr.2020.11.438