Predictive factors of hyperglycaemia in patients with parenteral nutrition

To identify the predictive factors of hyperglycaemia in patients receiving parenteral nutrition (PN). Retrospective observational study (January 2016- December 2016) conducted in a 450-bed university hospital. Adult hospitalized patients who received total PN through a central line for at least 48h...

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Bibliographic Details
Published in:Medicina clínica (English ed.) 2020-03, Vol.154 (5), p.157-162
Main Authors: Sangrador Pelluz, Cristina, Pardo Pastor, Júlia, Navas Moya, Elisabeth, Nicolás Picó, Jordi, Quintana, Salvador
Format: Article
Language:English
Subjects:
Aclaramiento renal
Critical patient
Diabetes mellitus
Hiperglucemia
Hyperglycaemia
Nutrición parenteral
Paciente crítico
Parenteral nutrition
Renal clearance
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Summary:To identify the predictive factors of hyperglycaemia in patients receiving parenteral nutrition (PN). Retrospective observational study (January 2016- December 2016) conducted in a 450-bed university hospital. Adult hospitalized patients who received total PN through a central line for at least 48h were included. The required variables to characterize patients, and those related to the PN received were collected and hyperglycaemia was defined as three consecutive glycaemias greater than 150mg/dl or two greater than 180mg/dl. A descriptive, comparative bivariate statistical analysis was carried out, as well as a multivariate analysis using binary logistic regression (SPSS.v.24.). 234 patients were included. The prevalence of hyperglycaemia in the population under study was 44.0%. The main differences observed in the bivariate analysis between hyperglycaemic and normoglycemic patients were related to age, previous comorbidities, medical department, presence of sepsis, duration and glucose contribution in PN, as well as blood glucose levels and corticosteroids. The predictors of hyperglycaemia obtained after the multivariate analysis were: renal clearance (OR=.982, 95% CI .968–0.996, p=.010), pre-PN glycaemia (OR=1.039, 95% CI 1.026–1.051 p
ISSN:2387-0206
2387-0206
DOI:10.1016/j.medcle.2019.05.012