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Vaccine effectiveness in patients admitted for influenza during the 2023–2024 season

Vaccination against influenza is widespread worldwide, reducing complications associated with infection. However, the impact of vaccination on mortality/ ICU admission in hospitalised patients has been little studied. A retrospective observational study was conducted on 238 patients hospitalised for...

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Published in:Medicina clínica (English ed.) 2024-12, Vol.163 (12), p.589-594
Main Authors: Ruzafa Martinez, Christian, Valero, Salvador, García Villalba, Eva, Tomás, Cristina, Muñoz, Ángeles, Alcaraz, Antonia, Martínez-Rodríguez, Rodrigo, Hernández, María Dolores, Martínez, María Isabel, Vicente, María Rosario, Guijarro Westermeyer, Elena, González Hipólito, Román, Bernal, Enrique
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Language:English
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Summary:Vaccination against influenza is widespread worldwide, reducing complications associated with infection. However, the impact of vaccination on mortality/ ICU admission in hospitalised patients has been little studied. A retrospective observational study was conducted on 238 patients hospitalised for influenza from October 2023 to January 2024 to evaluate the vaccine's effectiveness in terms of the combined event of ICU admission/mortality during hospitalisation. Additionally, the characteristics of vaccinated patients and the existence of bacterial superinfection were analyzed. Cox regression was performed using the SPSS program and the free "R" software. A total of 238 patients were included. Those vaccinated were older (78,2 ± 8,8 vs 69,97 ± 16,6 years; p 
ISSN:2387-0206
2387-0206
DOI:10.1016/j.medcle.2024.11.002