Microflow synthesis of fluorescent markers based on 1,8-naphthalimide for polylactide nanoparticles and bioimaging

[Display omitted] Two strategies for the synthesis of the new fluorescent markers based on 1,8-naphthalimide under classical conditions (in a flask) and in a microflow reactor are compared and contrasted. The microflow method provides higher purity of products, better productivity and production tim...

Full description

Saved in:
Bibliographic Details
Published in:Mendeleev communications 2020-11, Vol.30 (6), p.747-749
Main Authors: Oshchepkov, Maxim S., Semyonkin, Aleksey S., Menkov, Alexey O., Melnikov, Pavel A., Valikhov, Marat P., Solovieva, Inna N., Tkachenko, Sergey V., Malinowskaya, Julia A.
Format: Article
Language:English
Subjects:
1,8-naphthalimide
bioimaging
fluorescent markers
microfluidic synthesis
polylactide
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:[Display omitted] Two strategies for the synthesis of the new fluorescent markers based on 1,8-naphthalimide under classical conditions (in a flask) and in a microflow reactor are compared and contrasted. The microflow method provides higher purity of products, better productivity and production time. The resulting markers were used to obtain fluorescently labeled polylactide-based nanoparticles that can be used to study the distribution of polylactide nanoparticles as drug delivery vehicles within tissues and living organisms.
ISSN:0959-9436
DOI:10.1016/j.mencom.2020.11.019