Thiourea assisted recyclization of 1-(chloromethyl)dihydroisoquinolines: a convenient route to β-(o-thiazolylaryl)ethylamines

[Display omitted] 1-Chloromethyl-3,4-dihydroisoquinolines upon treatment with thioureas under acidic conditions undergo recyclization to afford new β-[o-(thiazol-4-yl)aryl]ethylamines.

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Bibliographic Details
Published in:Mendeleev communications 2021-01, Vol.31 (1), p.125-127
Main Authors: Zubenko, Alexander A., Morkovnik, Anatolii S., Divaeva, Lyudmila N., Demidov, Oleg P., Kartsev, Viktor G., Sochnev, Vadim S., Klimenko, Alexander I., Dobaeva, Natalia M., Borodkin, Gennadii S., Bodryakov, Anatolii N., Bodryakova, Marya A., Fetisov, Leonid N.
Format: Article
Language:English
Subjects:
1-chloromethyl-3,4-dihydroisoquinolines
2-arylethylamines
isoquinolines
recyclization
thiazoles
thioureas
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Description
Summary:[Display omitted] 1-Chloromethyl-3,4-dihydroisoquinolines upon treatment with thioureas under acidic conditions undergo recyclization to afford new β-[o-(thiazol-4-yl)aryl]ethylamines.
ISSN:0959-9436
DOI:10.1016/j.mencom.2021.01.040