New type of recyclization in 3,4-dihydroisoquinolines in the synthesis of β-(o-indazolylaryl)ethylamines and their 7-azaindazolyl analogues

[Display omitted] 1-(2-Hydrazinoaryl)-3,4-dihydroisoquinolines and their hydrazinopyridyl analogues undergo recyclization affording novel (7-aza)indazolyl-β-arylethylamines. The products are expected to possess neurotropic activities.

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Bibliographic Details
Published in:Mendeleev communications 2022-03, Vol.32 (2), p.265-267
Main Authors: Zubenko, Aleksandr A., Morkovnik, Anatolii S., Divaeva, Lyudmila N., Sochnev, Vadim S., Demidov, Oleg P., Klimenko, Aleksandr I., Fetisov, Leonid N., Bodryakov, Anatolii N., Bodryakova, Mariya A., Borodkin, Gennadii S.
Format: Article
Language:English
Subjects:
1-(2-hydrazinoaryl)-3,4-dihydroisoquinolines
7-azaindazoles
b-phenylethylamines
indazoles
Isoquinolines
recyclization
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Summary:[Display omitted] 1-(2-Hydrazinoaryl)-3,4-dihydroisoquinolines and their hydrazinopyridyl analogues undergo recyclization affording novel (7-aza)indazolyl-β-arylethylamines. The products are expected to possess neurotropic activities.
ISSN:0959-9436
DOI:10.1016/j.mencom.2022.03.038