Hybrid polycomplexes of anionic alginate with a synthetic cationic polymer: attractive and poisonous for microorganisms

[Display omitted] Negatively charged polycomplexes have been prepared by electrostatic complexation of synthetic cationic poly(diallyldimethylammonium chloride) with excess anionic sodium alginate. These polycomplexes exhibit pronounced antimicrobial activity due to the biodegradation of the alginat...

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Bibliographic Details
Published in:Mendeleev communications 2024-01, Vol.34 (1), p.31-33
Main Authors: Sinelnikova, Darya G., Novoskoltseva, Olga A., Loiko, Nataliya G., Nikolaev, Yury A., Yaroslavov, Alexander A.
Format: Article
Language:English
Subjects:
alginate
antimicrobial activity
microgels
negatively charged polycomplex
poly(diallyldimethylammonium chloride)
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Summary:[Display omitted] Negatively charged polycomplexes have been prepared by electrostatic complexation of synthetic cationic poly(diallyldimethylammonium chloride) with excess anionic sodium alginate. These polycomplexes exhibit pronounced antimicrobial activity due to the biodegradation of the alginate matrix and the release of the biocidal polycation. The results obtained are promising for the development of simultaneously attractive and toxic polymer constructs capable of destroying microorganisms.
ISSN:0959-9436
DOI:10.1016/j.mencom.2024.01.010