Occurrence of oxidative stress in dairy cows seropositives for Brucella abortus

Bovine brucellosis is an important zoonotic disease caused by the bacterium Brucella abortus that leads to economic losses due to animal discard and commercial restrictions. Since positive animals for brucellosis are culled, little is known about the pathogenesis of this disease. Therefore, the aims...

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Bibliographic Details
Published in:Microbial pathogenesis 2017-09, Vol.110, p.196-201
Main Authors: Perin, Géssica, Fávero, Juscivete F., Severo, Diego R.T., Silva, Anielen D., Machado, Gustavo, Araújo, Hugo L., Lilenbaum, Walter, Morsch, Vera M., Schetinger, Maria Rosa C., Jordão, Ricardo S., Stefani, Lenita M., Bottari, Nathieli B., Da Silva, Aleksandro S.
Format: Article
Language:English
Subjects:
Adenosine
Animals
Antibodies, Bacterial - blood
Biomarkers - blood
Brazil - epidemiology
Brucella abortus - pathogenicity
Brucellosis
Brucellosis, Bovine - blood
Brucellosis, Bovine - diagnosis
Brucellosis, Bovine - epidemiology
Brucellosis, Bovine - immunology
Catalase - blood
Cattle
Cattle Diseases - blood
Cattle Diseases - diagnosis
Cattle Diseases - epidemiology
Cattle Diseases - immunology
Cellular damage
Female
Inflammation
Oxidative Stress
Pregnancy
Seroepidemiologic Studies
Serologic Tests
Superoxide Dismutase - blood
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Summary:Bovine brucellosis is an important zoonotic disease caused by the bacterium Brucella abortus that leads to economic losses due to animal discard and commercial restrictions. Since positive animals for brucellosis are culled, little is known about the pathogenesis of this disease. Therefore, the aims of this study were to evaluate possible changes in the activity of deaminase adenosine (ADA) and the oxidative stress in cows seropositives for brucellosis (Experiment I), and to evaluate the seroprevalence of B. abortus in dairy cows from the Western state of Santa Catarina, Southern Brazil (Experiment II). The Experiment I evaluated 20 pregnant cows: ten seropositives for B. abortus and ten seronegatives that were used as controls. The ADA activity and markers of oxidative stress (TBARS, catalase (CAT) and superoxide dismutase (SOD)) were evaluated in these animals. A reduction in the activity of ADA and catalase enzymes in seropositive animals was observed (p 
ISSN:0882-4010
1096-1208
DOI:10.1016/j.micpath.2017.06.043