Nitrogen-doped polydopamine manganese nanoparticles with excellent oxidase-like activity for ultrafast detection of glutathione at room temperature

[Display omitted] •N-PDA@Mn showed high stability without usage of protectors.•N-PDA@Mn exhibited excellent oxidase-like activity.•GSH detection time was only 30 s for N-PDA@Mn-based strategy.•GSH detection break the temperature barrier for N-PDA@Mn-based strategy. Glutathione (GSH) is an essential...

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Bibliographic Details
Published in:Microchemical journal 2024-11, Vol.206, p.111606, Article 111606
Main Authors: Cai, Taimei, Liu, Feifan, Tian, Jianwen, Wen, Tao, Peng, Hailong
Format: Article
Language:English
Subjects:
Glutathione
Nitrogen-doped manganese nanoparticles
Oxidative-like activity
Ultrafast
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Summary:[Display omitted] •N-PDA@Mn showed high stability without usage of protectors.•N-PDA@Mn exhibited excellent oxidase-like activity.•GSH detection time was only 30 s for N-PDA@Mn-based strategy.•GSH detection break the temperature barrier for N-PDA@Mn-based strategy. Glutathione (GSH) is an essential natural antioxidant, and plays a crucial role in the prevention of various diseases. Herein, a nitrogen-doped polydopamine manganese nanoparticle (N-PDA@Mn) was prepared and used as nanozyme sensor for the rapid and colorimetric detection of GSH. N-PDA@Mn demonstrated excellent oxidase-like activity (Km = 0.0841 mM and Vmax = 3.6 × 10-7 MS-1), exhibiting a rapid balance period of 
ISSN:0026-265X
DOI:10.1016/j.microc.2024.111606