Nanosorbents in solid-phase extraction techniques for bioanalysis: A review

[Display omitted] •Different classes of nanosorbents are presented.•Applications in SPE, MSPE, DSPE, MEPS, TFME, µ-SPE, and SBSE are discussed.•Analytical figures of merit for each method are summarized.•Overview of nanosorbents in sample preparation is provided. In this article, we provide an in-de...

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Bibliographic Details
Published in:Microchemical journal 2024-12, Vol.207, p.112170, Article 112170
Main Authors: Yahaya, Noorfatimah, Mohamad Zain, Nur Nadhirah, Mohamed, Ahmad Husaini, Grasianto, Kamaruzaman, Sazlinda, Miskam, Mazidatulakmam, Jain, Rajeev, Raoov, Muggundha, Wan Abdullah, Wan Nazwanie
Format: Article
Language:English
Subjects:
Bioanalysis
Microextraction
Nanomaterials
Sample preparation
Solid-phase extraction
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Summary:[Display omitted] •Different classes of nanosorbents are presented.•Applications in SPE, MSPE, DSPE, MEPS, TFME, µ-SPE, and SBSE are discussed.•Analytical figures of merit for each method are summarized.•Overview of nanosorbents in sample preparation is provided. In this article, we provide an in-depth review of the application of nanosorbents for bioanalytical sample preparation. Based on the reported literature, researchers are increasingly interested in using nanomaterials to enhance conventional sorptive extraction methods and develop innovative techniques in bioanalysis. The properties, advantages, and disadvantages of various classes of nanosorbents used in bioanalytical sample preparation were discussed in this study. Detailed mechanisms of separation, green metrics evaluation, and the challenges and potential of nanosorbents in solid-phase extraction techniques are also elaborated. It is hoped that this review will assist researchers in the development of ideal techniques for selective, fast, green, simple, sensitive, and accurate analytical methodologies for bioanalysis.
ISSN:0026-265X
DOI:10.1016/j.microc.2024.112170