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A simple and efficient one-pot synthesis of 1,4-dihydropyridines using heterogeneous catalyst under solvent-free conditions

One-pot condensation of β-dicarbonyl compounds with aldehydes and ammonium acetate in the presence of HClO 4–SiO 2 at 80 °C under solvent-free conditions with good to excellent yields. The catalyst is easily prepared, stable, reusable and efficiently used under reaction conditions.

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Bibliographic Details
Published in:Journal of molecular catalysis. A, Chemical Chemical, 2006-12, Vol.260 (1), p.179-180
Main Authors: Maheswara, Muchchintala, Siddaiah, Vidavalur, Rao, Yerra Koteswara, Tzeng, Yew-Min, Sridhar, Chenchugari
Format: Article
Language:English
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Description
Summary:One-pot condensation of β-dicarbonyl compounds with aldehydes and ammonium acetate in the presence of HClO 4–SiO 2 at 80 °C under solvent-free conditions with good to excellent yields. The catalyst is easily prepared, stable, reusable and efficiently used under reaction conditions.
ISSN:1381-1169
1873-314X
DOI:10.1016/j.molcata.2006.07.024