Activation of CX (=Cl, Br) bond in aryl halides toward the palladium-catalyzed Heck reaction using 2,6-bis(diphenylphosphino)pyridine

The 2,6-bis(diphenylphosphino)pyridine, (Ph2P)2py, has been used to the palladium-catalyzed Heck coupling reaction of less reactive aryl chlorides as well as aryl bromides. [Display omitted] ► Application of a 2,6-bis(diphenylphosphino)pyridine, in Pd-catalyzed Heck reaction. ► Aryl chlorides afford...

Full description

Saved in:
Bibliographic Details
Published in:Journal of molecular catalysis. A, Chemical Chemical, 2013-01, Vol.366, p.30-35
Main Authors: Ataei, Ali, Nadri, Shirin, Rafiee, Ezzat, Jamali, Sirous, Joshaghani, Mohammad
Format: Article
Language:English
Subjects:
2,6-Bis(diphenylphosphino)pyridine
C[sbnd]C coupling
Heck reaction
Palladium catalyst
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The 2,6-bis(diphenylphosphino)pyridine, (Ph2P)2py, has been used to the palladium-catalyzed Heck coupling reaction of less reactive aryl chlorides as well as aryl bromides. [Display omitted] ► Application of a 2,6-bis(diphenylphosphino)pyridine, in Pd-catalyzed Heck reaction. ► Aryl chlorides afforded good to excellent yield of coupling products. ► The results of Heck reaction exhibited a high selectivity (>99/1) favoring the trans product. The 2,6-bis(diphenylphosphino)pyridine/palladium catalytic system successfully catalyzes the Heck coupling reaction of less reactive aryl chlorides as well as aryl bromides with styrene to give the corresponding olefins in reasonable yields. TBAB (tetrabutylammoniumbromide) as an additive was found to be essential for these reactions. The results of Heck reaction exhibited a high selectivity (>99/1) favoring the trans product.
ISSN:1381-1169
1873-314X
DOI:10.1016/j.molcata.2012.08.025