One-pot and two-step synthesis of novel carbonylthioureas and dicarbonyldithioureas derivatives

One-pot, two-step synthesis of several 1-cyclopropanecarbonyl-3-(substituted phenyl)-thioureas and 1-(phenylene-1,4-dione)-3,3′-(substituted phenyl)-dithioureas have been successfully prepared. The structures of the synthesized compounds were confirmed by elemental analysis, FT-IR spectroscopy and N...

Full description

Saved in:
Bibliographic Details
Published in:Journal of molecular structure 2015-11, Vol.1099, p.427-431
Main Authors: Banaei, Alireza, Shiran, Jafar Abbasi, Saadat, Afshin, Ardabili, Farnaz Fazlalizadeh, McArdle, Patrick
Format: Article
Language:English
Subjects:
Antibacterial activity
Carbonylthioureas
Dicarbonyldithioureas
X-ray crystallography
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:One-pot, two-step synthesis of several 1-cyclopropanecarbonyl-3-(substituted phenyl)-thioureas and 1-(phenylene-1,4-dione)-3,3′-(substituted phenyl)-dithioureas have been successfully prepared. The structures of the synthesized compounds were confirmed by elemental analysis, FT-IR spectroscopy and NMR. Also the crystal structure one of these compounds was determined by X-ray crystallography. All synthesized compounds were evaluated for antibacterial activity using Salmonella enterica (SE), Micrococcus luteus (ML), Bacillus subtilis (BS) and Pseudomonas aeruginosa (PS). •The new compounds of thioureas and dithioureas derivatives are synthesized.•The crystal structure one of these compounds was determined by X-ray crystallography.•The hydrogen bonding patterns in crystal structure are investigate.•All synthesized compounds were evaluated for antibacterial activity.
ISSN:0022-2860
1872-8014
DOI:10.1016/j.molstruc.2015.06.074