A near-infrared naphthofluorescein-based fluorescent probe for hydrogen sulfide detection

A simple naphthofluorescein-based probe was designed and synthesized by a two-step method. As expected, there was a good linear relationship between fluorescence intensity (680 nm)/absorbance (640 nm) and H2S concentration in the range of 2.00–10.0 μM with a detection limit of 0.50 μM/0.10 μM (S/N =...

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Bibliographic Details
Published in:Journal of molecular structure 2020-05, Vol.1207, p.127822, Article 127822
Main Authors: Chen, Weixing, Xie, Pu, Shan, Xixi, Zhao, Huaqi, Wu, Yao, Zhou, Hongwei, Jin, Xilang
Format: Article
Language:English
Subjects:
Cellular detection
Fluorescence
Hydrogen sulfide
Naphthofluorescein
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Summary:A simple naphthofluorescein-based probe was designed and synthesized by a two-step method. As expected, there was a good linear relationship between fluorescence intensity (680 nm)/absorbance (640 nm) and H2S concentration in the range of 2.00–10.0 μM with a detection limit of 0.50 μM/0.10 μM (S/N = 3). This probe was applied to monitor H2S concentration in red wine samples. Furthermore, it was successfully used to image exogenous H2S in living Hela cells, indicating its potential application in biology and medicine. [Display omitted] •A simple naphthofluorescein-based probe was designed and synthesized by a two-step method.•The probe exhibited high sensitivity, high selectivity, rapid response for H2S.•The probe was employed in red wine analysis with satisfactory results.•It was successfully used to monitor and image H2S in Hela cells.
ISSN:0022-2860
1872-8014
DOI:10.1016/j.molstruc.2020.127822