Immobilized nickel nanoparticles on modified magnetic titanium dioxide: A proficient and eco-friendly nanocatalyst for the green A3-coupling synthesis of propargylamines

• Published in: Journal of molecular structure 2024-06, Vol.1305, p.137727, Article 137727
• Main Authors: Moeini-Eghbali, Nasrin, Eshghi, Hossein
• Format: Article
• Language: English
• Subjects: A3-coupling; Magnetic catalyst; Ni nanoparticles; Propargylamine; Solvent-free reaction
• ISSN: 0022-2860; 1872-8014
• DOI: 10.1016/j.molstruc.2024.137727

•Modified magnetic titanium dioxide by immobilized nickel nanoparticles.•Full characterization of this novel catalyst using different techniques.•Synthesis of propargylamines via an A3 coupling reaction under solvent-free conditions.•The catalyst has high recyclability and stability. In this research, a novel and highly efficient magnetic catalyst was synthesized by surface modification of Fe3O4/TiO2 with epibromohydrine and N-(2-aminoethyl)piperazine linkers and then by immobilization of Ni nanoparticles onto the surface of magnetic titanium dioxide. The synthesized Fe3O4/TiO2-EP-NAEP/Ni nanocomposite was identified by FT-IR, PXRD, TEM, FE-SEM, ICP, EDX, TGA, and VSM techniques, and its catalytic performance was investigated in an A3 coupling reaction of amines, various aldehyde, and terminal alkynes in solvent-free conditions and propargylamine derivatives was gained with excellent yields. Also, the catalyst has high recyclability and can be reused at least six times in the synthesis of propargylamine derivatives with good yields. [Display omitted]