Red-emission, photobiological properties and antimicrobial photodynamic assays using mono-substituted corroles contain carboxylic acid and ester units

•Photophysical properties of meso-trans-A2B-type corroles containing COOH or COOMe units.•TD-DFT calculation analysis were conducted to better understand the corrole molecular structures.•Corrole COOH derivatives presents good photoactive with antibiotic association. The mono-substituted corrole der...

Full description

Saved in:
Bibliographic Details
Published in:Journal of molecular structure 2024-12, Vol.1318, p.139150, Article 139150
Main Authors: Oliveira, Morgana Maciél, Dantas, Gabrielle Aguiar, Costa, Luiz Antônio Sodré, Santos, Roberto Christ Vianna, Iglesias, Bernardo Almeida
Format: Article
Language:English
Subjects:
aPDT
Corroles, Photophysics
Microbiology
Photobiology
TD-DFT
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:•Photophysical properties of meso-trans-A2B-type corroles containing COOH or COOMe units.•TD-DFT calculation analysis were conducted to better understand the corrole molecular structures.•Corrole COOH derivatives presents good photoactive with antibiotic association. The mono-substituted corrole derivatives COOH-Cor and COOMe-Cor were obtained by Gryko methodology and characterized by microanaysis. In addition, we investigated experimental photophysical properties (absorption, emission by steady-state and time-resolved fluorescence) in some solvents and TDDFT calculations. Photobiological parameters such as aggregation, photostability and reactive oxygen species generation (ROS) was conducted. In addition, we also evaluated the preliminary antimicrobial photodynamic assays (aPDT) between studied corroles and bacteria strains, by white-light conditions. [Display omitted]
ISSN:0022-2860
DOI:10.1016/j.molstruc.2024.139150