Skin and soft tissue infections

Skin and soft tissue infections (SSTIs) range from common superficial skin infections to rare but life-threatening infections such as necrotizing fasciitis. They affect all ages. Predisposing factors include trauma, pre-existing dermatoses, diabetes mellitus and immunosuppression. SSTIs are often ca...

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Bibliographic Details
Published in:Medicine (Abingdon. 1995, UK ed.) UK ed.), 2017-11, Vol.45 (11), p.699-706
Main Authors: Ramsay, I.D., Török, M.E.
Format: Article
Language:English
Subjects:
Cellulitis
ecthyma
erysipelas
folliculitis
gas gangrene
group A streptococci
impetigo
MRCP
necrotizing fasciitis
skin and soft tissue infection
Staphylococcus aureus
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Summary:Skin and soft tissue infections (SSTIs) range from common superficial skin infections to rare but life-threatening infections such as necrotizing fasciitis. They affect all ages. Predisposing factors include trauma, pre-existing dermatoses, diabetes mellitus and immunosuppression. SSTIs are often caused by organisms that colonize the skin, such as Staphylococcus aureus or group A streptococci, because of a breach in the skin's integrity. Community-acquired meticillin-resistant S. aureus is increasingly recognized as a cause of SSTI. Treatment is usually with topical or systemic antimicrobials, directed against the suspected organism. Outpatient intravenous antibiotics are increasingly used, and new antimicrobials are emerging for use in these infections. Urgent surgical debridement is sometimes required.
ISSN:1357-3039
1878-9390
DOI:10.1016/j.mpmed.2017.08.008