Long-term remission of tumefactive relapsing multiple sclerosis after alemtuzumab rescue treatment in an adolescent patient

•Multiple sclerosis can present with tumefactive relapsing lesions.•Brain biopsy could help in differential diagnosis.•Alemtuzumab led to a sustained remission after 4 years of follow-up.

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Bibliographic Details
Published in:Multiple sclerosis and related disorders 2020-06, Vol.41, p.102061, Article 102061
Main Authors: Baroncini, Damiano, Annovazzi, P., Guaschino, C., Minonzio, G., Hametner, S., Stadelmann, C., Comi, G., Ghezzi, A., Zaffaroni, M.
Format: Article
Language:English
Subjects:
Adolescent
Alemtuzumab - therapeutic use
Antineoplastic Agents, Immunological - therapeutic use
Brain Neoplasms - complications
Brain Neoplasms - diagnostic imaging
Humans
Male
Multiple Sclerosis, Relapsing-Remitting - complications
Multiple Sclerosis, Relapsing-Remitting - diagnostic imaging
Multiple Sclerosis, Relapsing-Remitting - drug therapy
Treatment Outcome
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Description
Summary:•Multiple sclerosis can present with tumefactive relapsing lesions.•Brain biopsy could help in differential diagnosis.•Alemtuzumab led to a sustained remission after 4 years of follow-up.
ISSN:2211-0348
2211-0356
DOI:10.1016/j.msard.2020.102061