Evaluate of Different Bioactive Glass on Mechanical Properties of Nanocomposites Prepared Using Electrospinning Method

• Published in: Procedia materials science 2015, Vol.11, p.196-201
• Main Authors: Otadi, M., Mohebbi-Kalhori, D.
• Format: Article
• Language: English
• Subjects: Bioactive glass; Bone tissue engineering; Electrospinning; Electrospun nanocomposite scaffold; Poly(ɛ-caprolactone)
• ISSN: 2211-8128; 2211-8128
• DOI: 10.1016/j.mspro.2015.11.103

Electrospinning is a method in which materials in solution are formed into nano- and micro-sized continuous fibers under electrostatic field. This is especially important and forms one of the essential paradigms in the area of tissue engineering. Electrospun nanocomposite of Poly (ɛ-caprolactone) scaffolds incorporating the Bioglass (BG), have excellent performance in cell attachment and proliferation for bone remodeling. In this study, electrospun Polycaprolactone-Bioactive glass (BGs) nanocomposite were produced using electrospinning method. Three bioactive glass were selected based on SiO2-CaO-SrO-P2O5 system with exchange of SrO content was substituted for CaO and the other glass was 45S5. The morphology of electrospun nanofibers were evaluated using scanning electron microscopy (SEM). Data were statistically analyzed and compared between groups using ANOVA. The results revealed that BGs with a good dispersion and distribution in the nanofibers web increases the mechanical properteis compared with pure Polycaprolactone (PCL), but the 45S5 make more fragile the nanocomposite structure.