Fabrication and performance evaluation of rGO-PANI supported NiP/TMD based biosensors for electrochemical detection of dopamine

• Published in: Materials today communications 2024-03, Vol.38, p.107946, Article 107946
• Main Authors: Abhilash, S., Sarika, S., Ambadi, S., Akhila, M., Sumi, V.S., Sreekala, C.O., Rijith, S.
• Format: Article
• Language: English
• Subjects: Dopamine; Sensors; TMDs based NiMoP coating
• ISSN: 2352-4928; 2352-4928
• DOI: 10.1016/j.mtcomm.2023.107946

In this study, we present a novel approach for electrochemical sensing of DPA through the development of a unique electrode. It (WM-GP@NiMoP) composed of a mixed transition metal dichalcogenides (WS2-MoS2) supported by rGO and PANI, embedded via a facile electroless NiMoP plating technique. To evaluate the physico-chemical properties of the coatings, including phase analysis (X-Ray diffraction studies), morphology (Filed emission scanning electron microscopy), topology (Atomic force microscopy) and to assess the catalytic activity of the electrode for DPA sensing. The sensing behavior under various operating conditions, encompassing scan rate and pH of the analyte. The durability and performance evaluation were conducted to identify the consistent performance at an optimal pH value of 7 and it shown remarkable selective sensitivity and suppression of glucose and ascorbic acid interferences. The k0 values for the reversible electrode systems like dopamine was reasonable (5.3 ×10−10 cm/s) for the respective oxidation reactions. The CV analysis envisages the sensing potential of electrode towards DPA oxidation due to synergistic effect between PANI and rGO to MTMD on NiMoP coated electrodes. The work highlights the remarkable sensing capabilities of the WM-GP12 @NiMoP electrode in the field of electrochemical detection of DPA. Its exceptional sensitivity towards sensing of DPA establishes it as a significant advancement in electrochemical sensing technology. [Display omitted] •Synthesis of novel highly sensitive interference free DPA sensor.•The impact of precursors along with surface features was assessed.•Glucose and ascorbic acid interferences during sensing and LOD was investigated.•The sensor possesses desirable durability, repeatability and consistent performance.•Sensor showcase satisfactory detection of DPA in prepared sample