The vitro/vivo anti-corrosion effect of antibacterial irTENG on implantable magnesium alloys

Application of implantable triboelectric nanogenerator in vivo serves as a significant research route in self power medical facilities. In this research, we intended to settle the challenge of magnesium alloy implant corrosion protection in vivo. Here, we designed and fabricated a self powered corro...

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Bibliographic Details
Published in:Nano energy 2022-08, Vol.99, p.107397, Article 107397
Main Authors: Wu, Wenxiu, Guo, Naiyuan, Li, Wei, Tang, Chaokun, Zhang, Yixuan, Liu, Hao, Chen, Minfang
Format: Article
Language:English
Subjects:
Antibacteria
Cathodic protection
Implant corrosion protection
Implantable triboelectric nanogenerator
Magnesium alloy
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Summary:Application of implantable triboelectric nanogenerator in vivo serves as a significant research route in self power medical facilities. In this research, we intended to settle the challenge of magnesium alloy implant corrosion protection in vivo. Here, we designed and fabricated a self powered corrosion protection system based on implantable rectified Argentum electrode Polydimethylsiloxane and Titanium (PDMS-Ti) film TENG (irTENG). This irTENG successfully deaccelerated the corrosion rate of Mg-3Zn-0.2Ca alloy in a short term measurement and possess excellent antibacteria ability. The irTENG could reach the short circuit current of 14 μA and open currrent voltage of 175 V. In addition, the examine of 2 months raising SD rats revealed the favorable recovery after irTENG corrosion control system implantation surgery. Therefore, it represents the fine biocompability and feasibility of the irTENG in vivo application. On account of the performance of the irTENG corrosion protection system, the over quick corrosion issue of Mg alloy implant could be terminated and a novel application of TENG in biomedical field was proposed. [Display omitted] •The irTENG with good antibacterial ability was available in vitro and vivo anti-corrosion of Mg alloys.•With the protective effect of irTENG, the degradation rate of Mg alloys in vitro was reduced by 6.3% during 7 days.•Building a model of Mg-3Zn-0.2Ca implant degradation under irTENG protection in vivo.•This model successfully worked in vivo and no soft tissue damage was found around the Mg alloy.
ISSN:2211-2855
DOI:10.1016/j.nanoen.2022.107397