Results on accelerator production of innovative radionuclides for metabolic radiotherapy and PET and on related nuclear data

A range of high specific activity accelerator-produced radionuclides in no-carrier-added (NCA) form, for uses in metabolic radiotherapy and for PET, has been investigated. To this aim it was necessary optimizing the irradiation parameters by determining the excitation functions of the nuclear reacti...

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Bibliographic Details
Published in:Nuclear instruments & methods in physics research. Section A, Accelerators, spectrometers, detectors and associated equipment Accelerators, spectrometers, detectors and associated equipment, 2006-06, Vol.562 (2), p.1072-1075
Main Authors: Groppi, Flavia, Bonardi, Mauro L., Menapace, Enzo, Morzenti, Sabrina, Zona, Cristiano, Canella, Lea, Alfassi, Zeev B.
Format: Article
Language:English
Subjects:
Analytical–radioanalytical techniques
Metabolic radiotherapy
No-carrier-added radionuclides
PET
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Summary:A range of high specific activity accelerator-produced radionuclides in no-carrier-added (NCA) form, for uses in metabolic radiotherapy and for PET, has been investigated. To this aim it was necessary optimizing the irradiation parameters by determining the excitation functions of the nuclear reactions involved, as needed for the following selective radiochemical separations of the radionuclides of interest. For the NCA radionuclides investigated, the spectrometry measurements, done at LASA-INFN on γ, X and on α spectra are discussed together with the measurements of radionuclidic, radiochemical and chemical purities by analytical and radioanalytical techniques.
ISSN:0168-9002
1872-9576
DOI:10.1016/j.nima.2006.02.098